The best time to take loratadine is determined by the type of disease being treated. In the case of acute skin allergies, itchy skin conditions, etc., taking the medication during an attack is the best time to take it. If it is for the relief of chronic urticaria or allergic rhinitis, etc., the best time to take it is at bedtime. Loratadine can be taken to relieve chronic urticaria, itchy skin disease, allergic skin disease, etc. After taking the drug, some people may have adverse reactions such as fatigue, dizziness, drowsiness, etc. It is prohibited for people who are allergic to loratadine. 1. Chronic allergic diseases: if it is used for the treatment of allergic rhinitis, chronic urticaria, etc., it is recommended to take it at night before going to bed as the best time to take medication, taking medication before going to bed can avoid adverse reactions to the drug. 2. Acute attack allergic diseases: for acute urticaria, allergic skin diseases, itchy skin diseases, oral loratadine, need to take the drug in time when the disease attack. Loratadine needs to be taken under the guidance of a doctor, and cannot be taken on its own to avoid adverse reactions.