Sinusitis is a purulent inflammation of the sinuses, and the duration of headache cannot be generalized to patients with different types of disease. Sinusitis is caused by swelling of the mucous membrane in the sinus cavity or retention of secretions that irritate the trigeminal nerve endings by pressure, which can cause headaches. Sinusitis includes frontal sinusitis, maxillary sinusitis, septal sinusitis, and pterygoid sinusitis. Frontal sinusitis usually involves pain throughout the head, which increases in the morning, begins to decrease in the afternoon, and disappears at night. Maxillary sinusitis is less painful in the morning and more painful in the afternoon. In septal sinusitis, the headache is worst in the morning. Pterygoid sinusitis headaches are worse at night or after drinking. Patients with sinusitis can use antibiotics and medications that promote discharge of secretions, such as Chenault capsules, along with insistent use of saline to rinse the nasal cavity, which can usually provide effective relief. In addition, if medication has no significant effect, patients can undergo surgical treatment, such as negative pressure replacement method and sinus puncture surgery.