Patient: Description of condition (onset, main symptoms, hospital visited, etc.): I have been coughing for a long time and vomiting after coughing for more than a month, and I have severe anemia. I’ve been taking IVs and medication, but I can’t see any effect. Can you give me any advice on how to treat the cough? I hope our family can have a stable New Year. Mao Zhiguo: Uremia caused by polycystic kidney disease, dialysis for more than two years, cold and cough persist, accompanied by severe anemia and vomiting, there are the following points to consider: 1. Is the treatment not strong enough, or are the drugs chosen not targeting the causative organisms? Suggestions: chest X-ray or chest CT, blood routine, sputum culture + drug sensitivity test. We hope to clarify the infection and target the drugs. 2. The incidence of tuberculosis in uremic patients is quite high. Respiratory symptoms persist, attention should be paid to exclude the possibility of respiratory tuberculosis. Recommendations: tuberculin test PPD, anti-tuberculosis antibody test, diagnostic anti-TB treatment if necessary. 3. Is the combination with congestive heart failure and inadequate dialysis? Suggestions: strengthen dialysis ultrafiltration and strictly control blood pressure. 4. Severe anemia also has a great impact on the general condition, suggestions: actively correct anemia and treat with blood transfusion if necessary. It is recommended to communicate well with the doctor in the local hospital, and treatment can be started from the above aspects, and the next step will be decided according to the treatment response. Wish you a speedy recovery!