Treatment for gastric mucosa-associated tissue lymphoma includes anti-Helicobacter pylori (HP), chemotherapy, and surgery. Gastric mucosa-associated lymphoma is a non-Hodgkin’s lymphoma. The lesion originates from the mucosa-associated lymphoid tissue, with lymphoid follicles appearing in the submucosal layer, gradually spreading to the periphery and invading the whole layer. Patients often present with epigastric pain, nausea, vomiting and other discomforts. Currently, it is considered that the disease may be related to HP infection. Therefore, for early low-grade malignant gastric mucosa-associated tissue lymphoma in the presence of Helicobacter pylori infection, anti-HP treatment may be used, and the tumor may regress after complete HP removal. If antibiotic treatment is ineffective, there is a possibility of the existence of high malignancy, and CHOP regimen can be chosen for chemotherapy, and if necessary, surgical treatment for pathological staging. If you suffer from gastric mucosa-associated tissue lymphoma, it is recommended to go to a regular hospital to avoid delay.