Treatment of wheals is generally recommended to be more effective with antibiotic creams. Wheal edema occurs when Staphylococcus aureus enters the eyelash base through the opening of the blepharoplastid gland, leading to an infection of the sebaceous and blepharoplastid glands. Therefore, for the treatment of wheals, antibiotics such as levofloxacin eye drops and erythromycin eye ointment may be used. In addition, since the infection may spread, oral or injectable antibiotics against Staphylococcus aureus, such as erythromycin or cephalosporin antibiotics, are recommended if this occurs. The exact medication that should be used or whether other treatments should be administered is recommended under the guidance of a medical professional who will assess the impact of the severity of the condition, age, and other factors.