Intrahepatic glaucoma is an abnormal manifestation of ultrasound or CT of the liver. This condition may most commonly occur as a foci of intrahepatic calcification or intrahepatic bile duct stones. Intrahepatic calcified foci may be isolated lesions or may be a localized manifestation of certain lesions. Isolated foci of intrahepatic calcification can be observed with regular follow-up and do not require treatment. If the calcification foci are localized, it is possible that the lesion itself needs to be treated promptly. For example, primary hepatocellular carcinoma should be promptly considered for surgery or interventional treatment. Unlike intrahepatic calcified foci, intrahepatic bile duct stones are distributed along the intrahepatic bile ducts and may cause cholangitis, bile duct stenosis, liver atrophy or even cholangiocarcinoma as the lesion develops, even though there are no clinical symptoms at present. Therefore, the management of intrahepatic bile duct stones should be more aggressive, including not only the removal of stones, but also the removal of biliary strictures, removal of the already atrophied liver, and control of infection. However, some intrahepatic bile duct stones are caused by anatomical abnormalities and are therefore very difficult to prevent.