There is no optimal time for the treatment of gray nails, if we emphasize that the best time is to give timely prevention before the occurrence of gray nails. Early symptoms of gray nails, especially the free edge of the nail, should promptly remove the diseased part of the nail, and use antifungal medication topical application, you can apply topical amorphophallus application and so on. If the nail plate of the gray nail becomes gray, it must be treated with oral medication, which can be oral itraconazole or terbinafine, etc., and it can also be used with appropriate topical antifungal medication, such as amorphophane cream or amorphophane rub, etc., and at the same time, it is necessary to actively treat ringworm of the hands or feet, etc..