If there is a blister on the vulva, it may be caused by the following reasons: First, herpes simplex virus infection, which is more common in clinical practice, often due to the decline in the body’s resistance to viral infections, through laboratory tests can make the appropriate diagnosis, and give antiviral treatment. This kind of disease can be transmitted through sexual contact, so in the laboratory test did not turn negative before you can not have sex. Second, may be caused by herpes zoster, herpes zoster virus infection will lead to localized serious pain, in the clinical examination can also be diagnosed, and also recommended to give appropriate pain treatment, and to increase the body’s resistance, so that the virus can be removed in the body. Thirdly, if there are blisters on the vulva, it may be caused by drug allergy or sanitary napkin allergy, and the local itchy symptoms will appear, and after examination, the diagnosis can be clarified, and anti-allergy treatment can be given.