Urine protein 2+, occult blood 3+, other normal is mostly due to physiological factors such as strenuous exercise, specimen contamination, etc., and pathologic factors such as primary renal disease and secondary renal disease. 1. Physiological factors: such as after strenuous exercise and women’s menstrual period to take urine specimens are contaminated and so on, can lead to urine protein and occult blood physiological elevation. 2. Pathological factors: commonly found in primary kidney diseases such as glomerulonephritis, nephrotic syndrome, etc., as well as secondary kidney diseases such as hypertensive nephropathy, diabetic nephropathy, purpuric nephritis, lupus nephritis, etc., all of the above diseases may lead to proteinuria and urinary occult blood positivity. When patients find abnormal urine protein and occult blood, it is recommended to go to the hospital in a timely manner, follow the doctor’s instructions to carry out relevant examinations, identify the specific causes of the disease and then targeted treatment.