Rivaroxaban is an oral thromboprophylactic drug that acts as a factor X antagonist. It is used clinically for a variety of conditions that may lead to venous thrombosis, and is commonly used in orthopedics to prevent the possibility of deep vein thrombosis of the lower extremities that may occur after hip or knee replacement. The duration of the medication varies for different diseases. For hip replacement generally oral at least 3-5 days, knee replacement at least oral about 3 weeks. For the treatment of deep vein thrombosis in the lower extremities, anticoagulants are generally still taken orally for at least about 6 weeks after the clot has been reviewed as well as absorbed. As another example, thromboprophylaxis for atrial fibrillation may need to be taken for life. In addition, for patients who have had stents placed in their coronary arteries, the same antithrombotic medications will need to be taken for life. If bleeding occurs while taking the medication, then it is important to stop the medication immediately and seek medical help.