Children with long-term persistent constipation can improve their symptoms through lifestyle adjustments and medication, and specific treatment options need to be standardized under the guidance of a doctor. 1. Adjustment of lifestyle: It is recommended to drink more water, eat more food rich in dietary fiber, eat more fruits, eat a light diet, avoid spicy and stimulating food, regular work and rest, reasonable exercise, which will help improve the function of the gastrointestinal tract and the discharge of stool. 2. Medication: When non-pharmacological treatments have no obvious effect, you can use drugs such as Keserol and Lactulose to promote defecation and improve constipation under the guidance of your doctor, but the drugs should not be used for a long period of time. In addition, you can also follow the doctor’s instructions to use probiotics and other drugs to improve the function of the digestive system, such as bacillus subtilis bacillus granules and so on. In addition, there are other reasons (such as congenital megacolon, hypothyroidism, etc.) that can lead to persistent constipation in children, and it is recommended to go to the hospital in time to get a clear diagnosis and then carry out targeted treatment to avoid delaying the treatment time. All of the above drugs should be used under the guidance of a doctor.