Perianal eczema is generally associated with local stimulation, heredity and other factors, the treatment mainly includes general treatment and drug therapy. 1. General treatment: regulate diet, avoid spicy stimulation, clear allergic food, improve living habits, avoid sedentary, pay attention to personal hygiene, and avoid all kinds of external stimuli that may cause the disease, such as excessive scratching, washing and wiping, dampness, accumulation of perspiration. 2. Medication: including local topical medication (such as boric acid solution, glucocorticoid cream / ointment, etc.), oral medication (mainly antihistamines, used to relieve itching, commonly used loratadine, ibastine, etc.), acute episodes of short-term use of hormones, such as prednisone orally. Perianal eczema is prone to recurrent attacks, long lasting, its treatment and medication should also be under the guidance of a physician to follow the doctor’s instructions, and regular follow-up.