What is the best material to use for cranial bone repair? Cranium plays a very important role in the human body, not only maintaining the integrity of the whole head, but also protecting the brain and the sensory organs of the head. However, there may be many dangerous factors in daily life that threaten the normal and integrity of the skull and the life and health of human body. For example, some traffic accidents, production accidents, cranial surgery, etc. may lead to cranial defects. Cranial defects can cause many hazards to human body, so cranial repair surgery should be performed promptly after cranial defects. The repair material was made of plexiglass in the early days, and there was no access at that time, so we went to the street and bought a piece of plexiglass to shape it. There are patients who have been in peace for more than 40 years without any change, but its disadvantage is that it is more brittle and poorly shaped. Secondly, silicone, silicone, as we all know, is used more in beauty salons. Silicone has also been used in clinical practice for about one or two decades, and the results are good, but it is not strong enough and easy to accumulate fluid. Titanium mesh is commonly used in skull repair surgery. In many areas where the economy, technology and information are not developed, local hospitals mostly use titanium mesh to make bone plates. The titanium material is a precious metal, which is not only expensive, but also prone to postoperative complications. For example, in the CT and MRI examination and diagnosis will have a certain impact on the test data, and in the hot and cold test, some patients will have pain and other adverse symptoms in their bodies. Moreover, the titanium bone plate needs to be fixed with titanium nails, and in patients with thin scalp, the bone plate will protrude and have no aesthetic appearance. The material commonly used in clinical practice today is polyetheretherketone (PEEK) is a highly desirable cranial replacement material. It has properties in elasticity, stiffness, thermal insulation, stability, etc., and human skull box single, and it can be customized in three dimensions, precisely anastomosing the defect area, and highly fused with the autologous skull, with very good repair results.