Low levels of total protein, albumin and globulin indicate that the entire body is in a very deficient state of protein, as seen in the following disease states: 1. Patients who have been eating poorly for a long time and are in a state of malnutrition will also experience a significant decrease in protein levels, accompanied by swelling. 2. The liver is the main organ of protein synthesis, but when the liver function is abnormal, the entire albumin level of the human body, whether total protein or globulin, will be significantly reduced. 3, kidney lesions, especially in nephrotic syndrome, due to the loss of a large amount of protein from the urine in the body after kidney lesions, will also cause a decline in the human protein level, including total protein and globulin is also decreased, the patient accompanied by obvious swelling. If the protein level is low, the patient should be examined from the above causes to clarify the cause of low protein before targeted treatment.