Do blood pressure medications have an effect on liver function

In general, drugs that control blood pressure have an effect on liver function. The liver acts as the body’s metabolic factory, where almost all blood pressure-related drugs are metabolized.
In general, antihypertensive drugs commonly used in clinical practice are divided into five categories, namely diuretics, beta-blockers, calcium channel antagonists, angiotensin receptor antagonists, and angiotensin II receptor antagonists. Most of these drugs are metabolized in the liver and excreted in the kidneys. Therefore, long-term use will have some effect on liver function. They should be used with caution in patients with abnormal liver function.
In addition, some of the drugs to control blood pressure also have a certain impact on renal function, renal insufficiency patients need to be rationally used under the guidance of the doctor.