Lupus nephritis type IV is more serious. Lupus nephritis type IV refers to diffuse lupus nephritis with greater than 50% or more kidney involvement, which is a more serious type. The common clinical manifestations of patients with lupus nephritis type IV are proteinuria and hematuria. Some patients also have different degrees of renal function impairment, and the serious condition may even develop into uremia. Some patients with lupus nephritis type IV will have more serious pathological features such as crescent, capillary endothelial cell proliferation, fibrinoid necrosis, etc. Therefore, patients with lupus nephritis type IV should be actively treated under the guidance of doctors. For patients with lupus nephritis, it is recommended to consult a doctor in time. Clinically, large doses of hormones are often used in conjunction with immune preparations for treatment, and the specific treatment plan should be reasonably selected under the guidance of a professional doctor, and do not self-medication.