The gallbladder is located in the upper right abdomen below the liver. After inflammation of the gallbladder, patients may experience pain in the upper right abdomen, which may be vague or dull when symptoms are not severe. Typical patients may present with biliary colic, which manifests as pain in the right upper abdomen and radiates to the back of the right shoulder. Some patients may not feel pain in the right upper abdomen and have a sinking in the right shoulder, at which point the presence of a gallbladder problem is determined by ultrasound. Some patients often feel pain in the upper abdomen or even have stomach pain, undergo gastroscopy and go to the gastroenterology department to prescribe medication, and if the effect is not satisfactory after taking it, the patient should visit the hospital to determine whether there is a gallbladder problem, and determine whether there are stones and inflammation in the gallbladder through abdominal ultrasound. The location of pain in gallbladder lesions usually occurs in the right upper abdomen, but not exclusively. Some people may present with angina pectoris, and some patients with gallstones feel pain in the right upper abdomen and also have chest tightness, which may be considered after an electrocardiogram examination for the presence of a heart attack. Therefore, the clinical manifestations of cholecystitis are varied and do not appear the same in different people. Patients must not take it lightly in clinical practice and should seek prompt medical attention when they feel unwell. Although right upper abdominal pain is present, some patients may also have angina pectoris, so epigastric pain and angina pectoris need to be differentiated.