The body always feel tired and exhausted may be physiological factors, neurasthenia, depression and other causes. 1. Physiological factors: If the patient in the long-term mental, work stress, irregular work and rest, short sleep and other physiological factors, there may be a body old tired tired phenomenon. 2. neurasthenia: neurasthenia is a disease of nervous system dysfunction, is due to a long time in the mental tension, excessive pressure and other circumstances triggered by a psychological disease. Neurasthenia will make the patient sleep well so that the body always feel tired and fatigue symptoms. 3. depression: depression belongs to the affective mental disorder or mood disorder disease, manifested in persistent interest decline, depressed mood, etc., so that the patient appeared to the phenomenon of the body always feel tired and fatigue. When the patient has the phenomenon of tiredness and fatigue, it is recommended that timely medical examination to determine the cause of the disease, under the guidance of the doctor to actively cooperate with the treatment.