There is a relationship between occupation and the development of urolithiasis. The incidence of urolithiasis varies among people engaged in different occupations. The development of modern science has led to an increase in the number of people engaged in mental labor, but also changed the incidence of urolithiasis. Workers engaged in the following occupations are more susceptible to urolithiasis: 1, high-temperature conditions workers cooks, boilermakers and others who work in hot environments. This is related to sweating more and concentrating urine in a hot environment. 2, brain workers managers, office workers and seafarers and other economic income is relatively high, less active personnel. For example, the incidence of urolithiasis in seafarers is higher than that of sailors. 3, physicians (especially surgeons) physicians suffering from urolithiasis is also more. 4, flight personnel in the air force and airlines in the incidence of kidney stones in the flight personnel than the ground staff 3.5 ~ 9.4 times higher, which is mainly related to the pilot’s diet of high animal eggs from and high cholesterol. The word astronauts in space flight period, due to the activities of less, diet to high protein-based, drinking less water, and vomiting and urine concentration; in the case of weightlessness in the layer of liquid calcium oxalate and phosphate in the over he and degree increase, urinary pH is reduced and the structure of the reduction of citric acid, and other factors are conducive to the formation of calcium oxalate and uric acid stones. 5, with his, Fu, lead have contact with some special occupations can cause kidney damage and cause the risk of kidney stone formation increased. 6, industrial workers engaged in agricultural labor than those engaged in industrial labor, the incidence of protolithiasis is low.