The esophageal mucosal damage caused by radiotherapy is also known as radiation esophagitis, which can be mainly treated with medication and surgery to eliminate inflammation and repair the esophageal mucosa. 1. Drug treatment. All medications should be used under doctor’s guidance, and if there are any uncomfortable symptoms, it is necessary to consult the doctor in time. (1) Drugs to protect the esophageal mucosa. Drugs such as aluminum thioglycollate have a certain protective effect on the esophageal mucosa, thus relieving symptoms. (2) Drugs to relieve esophageal smooth muscle spasm. Such as nifedipine and other calcium antagonists, can relieve esophageal smooth muscle spasm and reduce pain. (3) Proton pump inhibitors. Such as omeprazole can prevent acid reflux from aggravating the damage of esophageal mucosa. (4) Glucocorticoid drugs. Such as aminotriol ketoglutarate (prednisone), etc., can play the role of anti-inflammatory, reduce radiation damage, relieve symptoms and so on. (5) Nutritional support drugs. Such as intravenous nutrient solution, enteral nutrient solution, etc., can provide the nutritional support needed by the body when the condition is more serious. 2. Surgical treatment. Including esophageal balloon dilatation, esophageal stent implantation, esophageal tracheal fistula repair, etc., which can dilate the esophagus, seal the fistula, to avoid serious complications such as esophageal perforation, and can rebuild the structure of the esophagus. It is recommended that the people concerned should consult the doctor in time and be treated according to their specific conditions.