A single surviving kidney puncture for 3 months is able to be vaccinated with the new crown vaccine, but the purpose of kidney puncture needs to be clarified, and the patient is currently suffering from the disease to judge. 1. Renal puncture and renal biopsy are performed to clarify the diagnosis, check the treatment effect and improve the next treatment plan. If it is clear that the patient does not have any special disease or the disease has been effectively controlled after 3 months of renal puncture, the patient can be vaccinated with New Crown Vaccine if other contraindications are ruled out. 2. If the diagnosis is clear after renal puncture, and the patient is in the acute exacerbation stage (acute nephritis, IgA nephropathy, etc.), and the disease has not been effectively controlled, and further treatment is needed, it is not recommended to vaccinate the new crown vaccine for the time being. Whether the specific vaccination is possible also needs to consider the patient’s own condition, the severity of the disease and other factors, so it is recommended that the patient go to a regular hospital department for consultation and consultation, determined by a professional physician after a comprehensive assessment, do not blindly vaccination.