The skull plays an important protective role. When the human skull is damaged for various reasons, the soft tissues inside the skull will lose strong protection, so timely skull repair is needed to maintain the integrity of the skull and to enable the soft tissues inside the skull to function normally in order to better protect one’s overall health. When it comes to skull repair, many people’s first impression will be that it is a relatively high-risk surgery, so they have been hesitant to go for it, thus delaying the better time for skull repair. As early as the beginning of last century, our medical predecessors had already been practicing cranial repair surgery, but the results were not very satisfactory because the technology at that time was relatively crude and the materials were relatively simple. Later on, the fear of cranial repair surgery in people’s mind was increased due to some problems such as infection, rejection and exposure that may occur after the clinical use of repair materials. In the long run, in the perception of patients with cranial defects, it will be considered as an extremely risky surgery. In fact, under the trend of rapid development of modern medicine, cranioplasty has become a widely used routine procedure in neurosurgery with quite mature experience. In fact, during the development of cranial repair, cranial repair materials have also undergone continuous innovation and progress. Nowadays, polyetheretherketone peek, which is widely recognized and highly promoted by the medical community, is a very ideal repair material. This material is excellent in terms of shaping, thermal insulation, strength, as well as in terms of anti-infection and anti-rejection. In addition this material preoperatively according to the three-dimensional shaping of polyetheretherketone PEEK repair piece, can be very good with the size of the patient defective bone window, and postoperative no rejection reaction, and will not interfere with CT, nuclear magnetic examination.