Cranial repair is a procedure with a very long history, with our ancestors performing such surgical practices thousands of years ago. After a long period of development and historical evolution, cranioprosthetic surgery is now a relatively routine procedure in modern medical conditions, and the technique is very mature and widely performed. One of the factors that have a great impact on the outcome of the repair is the choice of cranial repair materials. The traditional materials such as plexiglass, bone cement, silicone, etc. are no longer used in clinical practice because of various defects. At present, titanium mesh is the most widely used cranial bone repair material in most hospitals, but this material also has certain defects, such as postoperative infection and rejection, hot and cold sensitive reaction, easy to deformation by force, affecting CT magnetic examination and so on. Now there is a more advanced material called polyetheretherketone peek material. Polyetheretherketone peek material is a new type of special polymer material with very good performance, which overcomes the problems that may be produced by titanium mesh material and can achieve very good repair effect when applied in cranial bone repair. peek material is very close to human own cranial bone in terms of hardness, elasticity, heat insulation, histocompatibility, plasticity, etc. At the same time, it can be shaped according to the shape and structure of the patient’s skull, which can restore the appearance of the skull to a high degree. It is the best material for skull repair.