I. Initialization of the device (Before using the product for the first time, the DuPont device must be initialized). Unscrew and pull out the cap, making sure the red screw handle is underneath. Hold the DuPont straight up, grip the red handle and the middle part of the DuPont, and rotate it to the end in one direction, and then to the end in the opposite direction. You will hear a “click” once during this process. Repeat step 2 once. Note: Do not exhale into the suction nozzle. Screw on the cap after each use. Do not disassemble or install any part of the device. As the dose of powder is small, you may not feel it each time you inhale, however, if you follow the above steps, then you can be sure that you have inhaled the required dose. Please wipe the mouthpiece regularly (once a week) with a dry paper towel. Do not scrub the outside of the nozzle with water or liquid. C. Precautions during the use of the medicine 1. After each time you inhale the medicine, please rinse your mouth with water to reduce the possibility of fungal oropharyngitis. 2.You need to gradually reduce the dose when you stop using this product, and you should not stop using it suddenly. 3.If you find that the treatment is not effective, or the required dose exceeds the maximum recommended dose of this product, you should seek medical help. 4. Carry a fast-acting bronchodilator with you (for patients using this product as maintenance therapy). 5. Inhale maintenance doses of this product as prescribed, even when asymptomatic. 6.Once asthma symptoms are controlled, consider gradually reducing the dose of Cymbicort. 7.Shinbeck treatment should not be started during an acute asthma attack or when symptoms are significantly worse or acutely worsened. 8.If wheezing worsens immediately after inhalation of the drug, stop using the product and seek medical help. 9.Systemic effects can occur with any inhaled corticosteroid, especially when used for long periods of time and at high doses. The incidence of these effects is much lower with inhalation therapy than with oral corticosteroids. Possible systemic effects include adrenal suppression, growth retardation in children and adolescents, decreased bone mineral density, cataracts and glaucoma. 10. Children and adolescents with long-term corticosteroid use should be closely followed for growth. 11. For those patients who also have other risk factors for osteoporosis, the potential effects on bone density should be considered when using this product at high doses for a long time. 12.Use with caution in athletes. 13, The most common adverse reactions are tremor and palpitations, these reactions are usually mild and disappear within a few days after treatment.