Pregnancy is the happiest time in a woman’s life, but it also causes some changes in the pregnant mother’s body due to the state of pregnancy, and likewise makes the incidence of some diseases higher and higher. Here we will talk about gestational diabetes, a common endocrine disease during pregnancy. 1. What is gestational diabetes mellitus? Diabetes mellitus during pregnancy is divided into two categories: one is diabetes mellitus that has been diagnosed before pregnancy or found for the first time during pregnancy and the elevated blood sugar has reached the standard of diabetes mellitus, which is called pre-pregnancy diabetes mellitus, also called diabetes mellitus combined with pregnancy; the other is diabetes mellitus during pregnancy when everything is normal before pregnancy and the abnormal glucose metabolism occurs during pregnancy. 2. What are the diagnostic criteria for pre-pregnancy diabetes mellitus? (1) Patients who have been diagnosed with diabetes mellitus before pregnancy. (2) Pregnant women who have not undergone glucose testing before pregnancy and have elevated blood glucose at the first prenatal examination meeting any of the following criteria Fasting glucose ≥7.0mmol/L. 75g oral glucose tolerance test (OGTT), blood glucose ≥11.1mmol/L 2h after taking sugar. With typical hyperglycemic symptoms or hyperglycemic crisis, along with random blood glucose ≥11.1mmol/L. Glycosylated hemoglobin (HbA1c) ≥6.5%. 3. What are the diagnostic criteria for gestational diabetes mellitus? A 75g oral glucose tolerance test (OGTT) is performed at 24-28 weeks of gestation, and venous blood is drawn before, 1 hour and 2 hours after taking sugar, and the reference values of the three times are 5.1mmol/L, 10.0mmol/L and 8.5mmol/L, respectively, and any of the measured values meet or exceed the above criteria can be diagnosed as gestational diabetes. 4. How is gestational diabetes treated? Most patients with gestational diabetes can normalize their blood glucose through diet, exercise and other lifestyle interventions. Patients with unsatisfactory results are recommended to use insulin to control their blood glucose, which is a large molecular protein that does not affect the fetus through the placenta. At present, there is a lack of relevant research on the safety of oral hypoglycemic drugs in China, and their use is not recommended.