The main manifestations of hypertensive nephropathy are high blood pressure, edema, proteinuria, renal failure, etc. When the above symptoms appear, you should seek for medical treatment in time. 1. Hypertension: Patients with hypertensive nephropathy usually have symptoms of hypertension first, such as headache, dizziness and other common symptoms of hypertension. 2. Edema: Generally, there is generalized edema with depression on finger pressure, and there can be edema of eyelids, face, and both lower limbs. 3. Proteinuria: the patient’s kidney is in high perfusion state for a long time, which leads to proteinuria, clinically visible urine foam becomes more, and urine routine test suggests that the protein in the urine is abnormal. 4. Renal failure: long-term sustained hypertension increases the pressure of glomerular capsule, glomerular fibrosis, atrophy, renal arteriosclerosis, resulting in ischemia of renal parenchyma and decreasing renal units, glomerular filtration rate decreases, and blood creatinine increases. Patients with hypertensive nephropathy should go to regular hospitals in time and under the guidance of physicians for standardized treatment.