Hidden pain of kidney stone may be related to many factors such as kidney stone obstruction, stone infection, ureteral spasm, etc. It can be treated with drugs such as ibuprofen extended-release capsules, diclofenac sodium enteric-coated tablets, celecoxib capsules, atropine sulfate tablets, etc. under doctor’s guidance. 1. Kidney stone obstruction: when the stone causes ureter blockage, the urine produced by the kidney can not be discharged out of the body, which may cause hydronephrosis. With the gradual aggravation of hydronephrosis, the pressure of the kidney will be increased, which will stimulate the peritoneum outside of the kidney to appear painful sensation. It can be treated with drugs such as ibuprofen extended-release capsule and celecoxib capsule under doctor’s guidance, and should be actively treated with surgery. 2. Stone infection: Infection caused by kidney stones may cause pyelonephritis, which may cause pain, and can be treated with diclofenac sodium enteric-coated tablets, celecoxib capsules and other medicines under doctor’s guidance; when the infection is expelled or the body can tolerate the surgery, it should be operated to expel the stones out of the body. 3. Ureteral spasm: spasm can cause stimulation of the peripheral nerves and then the phenomenon of pain, can be prescribed to use atropine sulfate tablets, scopolamine tablets and other drugs to relieve spasm. Kidney stone pain may have other causes, should immediately go to the hospital, clear cause and give targeted treatment.