In the current era of family planning policy, one-child families have become the mainstream, and one or two children have become an important link between two generations of parents and the whole extended family, so for a healthy and smart baby, we are paying more and more attention to pre-conception checkups. Many mothers and fathers-to-be have started to prepare for their future babies. Generally speaking, the pre-pregnancy preparation can be divided into work-life preparation, physical preparation and psychological preparation, work-life is mainly for the “October pregnancy” and nearly half a year of breastfeeding to plan and create a safe and comfortable pregnancy environment. For example, those who are exposed to toxic radiation in the workplace should leave the workplace first, those who have pets at home should be given away temporarily, and those who are exposed to intense exercise or labor should avoid it. The psychological aspect is mainly a role adjustment, for the sake of a healthy baby to have “suffer” psychological preparation, convince themselves to change some bad habits, such as smoking, alcohol, staying up late, etc., to develop some good habits and behavior, such as more exercise, more tolerance, more optimism; regular diet and rest, etc. Here we focus on the physical aspects of preconception preparation, because this is the most closely related to the health of the baby. Pregnancy is a matter for both spouses, which requires both of them to go for checkups; any problem with either of them can cause infertility, miscarriage, fetal malformation and other problems. Of course, since the woman has to bear the burden of pregnancy and delivery, the female partner takes a more important place in the preconception checkup. This is not only for the healthy development of the fetus, but in fact, the pregnancy process itself is a physiological stressful process for the woman, which requires a more comprehensive examination and evaluation in order for her to pass this special period safely. First of all, pregnancy is a great challenge for women. With the increase in metabolism throughout the process, there are great changes in all systems of the female body, especially the circulatory system, blood system, urinary system and digestive system are under a particularly heavy burden, so it is especially important to assess the heart function, liver and kidney function through a medical examination. If these diseases are combined during pregnancy, they can lead to miscarriage, premature birth, stillbirth, fetal growth restriction, fetal distress and neonatal asphyxia, and the life of the pregnant woman can be at risk. If you have not had a comprehensive medical checkup in the last year, you must go to a regular hospital for a medical checkup because many diseases are asymptomatic in the early stages and can only be detected and treated early through various auxiliary examinations. Routine physical examination includes: routine blood, routine urine, electrocardiogram, blood pressure, blood lipid, blood sugar, liver and kidney function, abdominal ultrasound, gynecological examination, breast examination, etc. These basic examinations can detect many internal diseases, such as hypertension, heart disease, diabetes, anemia, etc. If you suffer from these diseases and become pregnant without knowing, it can seriously endanger the health of mother and child, and even endanger your life. However, if these diseases are found before pregnancy, they should be treated first and then have a baby if they get better after treatment and ensure that they can get pregnant. After pregnancy, it is also important to strictly use medication and do regular prenatal checkups under the guidance of a professional doctor to closely monitor the health status of the mother and child. If a man has not had a medical checkup within a year, he should also go to a regular hospital for a medical checkup, and any diseases found should be treated in a timely manner, and men bear the unshirkable responsibility of raising a baby, and only if they are in good health can they do their role as a father. Genitourinary system examination: Gynecological examination is particularly important in the preconception examination, through which we can find out: whether there are inflammatory infections, such as: mycobacteria, trichomonas, chlamydia infection, etc.; whether there are genital malformations, such as: vaginal longitudinal septum, double uterus, stump uterus, etc.; whether there are sexually transmitted diseases, such as: gonorrhea, condyloma acuminata, genital herpes, etc.; whether there are tumors, such as: cervical cancer, uterine fibroids, ovarian tumors, etc. If you have these diseases, you must be treated first! Otherwise, pregnancy with disease not only brings great inconvenience in terms of treatment, but also affects the health of the fetus, and sometimes even has to be aborted, such as vaginitis can cause intrauterine infection, late miscarriage, premature birth, stillbirth, neonatal infection, etc.; tubal stricture can lead to ectopic pregnancy; double uterus leads to infertility, miscarriage, premature birth, fetal growth restriction, etc.; gonorrhea can lead to neonatal gonorrheal conjunctivitis, pneumonia, and even gonorrhea Sepsis, so that the perinatal mortality rate increases significantly; uterine fibroids can lead to infertility, tumor malignancy, etc. The male examination mainly includes whether there are abnormalities in the genitourinary system, whether the sexual function is normal, etc., and most importantly, whether the semen is normal. This is because the most important thing for men in the process of pregnancy is to provide healthy sperm to participate in fertilization. Infectious diseases, eugenics, genetics examination: infectious disease examination mainly includes hepatitis B and sexually transmitted diseases, because these two have the greatest impact on pregnancy and family, it is recommended that both couples before pregnancy should also do hepatitis B and a half, HIV, syphilis, gonorrhea, condyloma acuminata and other diseases, hepatitis B and a half, can be examined together with liver function (liver function test of general physical examination does not include hepatitis B and a half), pregnancy In early pregnancy, viral hepatitis in women can aggravate the pregnancy reaction, and the incidence of miscarriage and fetal malformation is about two times higher than normal. The combination of viral hepatitis in late pregnancy can increase the incidence of hypertensive disorders in pregnancy and the incidence of postpartum hemorrhage. Hepatitis virus can also be transmitted vertically to the newborn through the placenta. Patients with chronic hepatitis are less symptomatic in the inactive phase, so this test is important. The most common type of viral hepatitis is viral hepatitis B. There are no specific antiviral drugs available, so if you are tested positive, you must visit the infectious disease department before pregnancy to ensure that your liver function is normal before conceiving, and you should be closely monitored throughout the pregnancy because the physiological changes and metabolic characteristics of pregnancy can make viral hepatitis worse. For HIV, syphilis and other sexually transmitted infections, the risk of pregnancy is even greater, not only can be transmitted to the child, causing abnormalities, stillbirth or premature death, these diseases also greatly endanger the health of the couple, it is worth mentioning that men are often recessive carriers of sexually transmitted diseases, they do not have obvious clinical symptoms, but can be transmitted to their sexual partners, causing the female partner to develop, so the male partner should pay more attention to the examination of these diseases. Eugenics genetic testing is mainly for people whose work and living environment can affect pregnancy or those who have a history of bad fertility. If you have pets at home, you should undergo a full set of detoxification tests, including rubella, toxoplasmosis, cytomegalovirus and monovirus, also known as TORCH (also known as eugenics four), which have common characteristics, that is, they can cause mother-to-child infection. Due to endocrine changes and decreased immunity in pregnant women, potential viruses in previously infected pregnant women are easily activated and recurrent infections occur. When viremia occurs in pregnant women, the virus can spread through the placenta or birth canal and infect the fetus, causing premature birth, miscarriage, stillbirth or fetal malformation, as well as causing damage to multiple systems and organs in the newborn, even leading to mental retardation and other malignant consequences. Therefore, those whose tests show active infection must be treated before pregnancy. For women with a history of previous adverse births (e.g. spontaneous abortion, gravida, ectopic pregnancy, stillbirth, malformation, premature birth, unexplained death of the infant after delivery), it is important to combine the medical history with the relevant common causes and to perform tests for infection, endocrine, chromosomal and reproductive immunity, as appropriate, otherwise it is likely that the next pregnancy will produce the same results as the last one. The chromosomal abnormality of both partners is a common cause of miscarriage, abnormality and even stillbirth, and karyotype analysis of peripheral blood of both partners is recommended for couples with recurrent spontaneous miscarriage and stillbirth. This is most common in cases where the mother is type O and the fetus is type A or B. If the RH blood type does not match, hemolysis is likely to occur in the second child. Most of the above mentioned tests are performed in the first 3 months of pregnancy. It is not an easy task to conceive a baby, but it is worthwhile to carry out these tasks for the health of the baby, as well as the happiness of the family. Having said that, I am sure you understand the importance of preconception tests and that it is the responsibility of both the couple. After doing so many tests, you should also accept the doctor’s eugenic guidance, such as: avoid exposure to radiation, electromagnetic radiation, etc.; avoid working in high temperatures; avoid noise; avoid exposure to heavy metals such as lead, mercury, arsenic, benzene, etc.; avoid exposure to pesticides, tobacco and alcohol, etc. Then put your heart and soul into “making a man” activities, I believe that you will be able to have a healthy baby and a warm family soon.