The most effective treatment for atherosclerosis is not a scientific statement. Atherosclerosis need to be under the guidance of the doctor, according to the condition of the choice of appropriate treatment, such as drug therapy, surgical treatment, control of risk factors and so on. 1. Drug therapy: mainly regulating blood lipid therapy, antiplatelet therapy, anticoagulation can be used in acute occlusion of blood vessels, and so on. (1) Antiplatelet therapy commonly used drugs such as aspirin, clopidogrel, etc., which helps to prevent the development of vascular occlusive lesions, used to prevent coronary heart disease and cerebral artery thromboembolism. (2) Anti-coagulation and thrombolytic therapy are commonly used in acute occlusion of blood vessels, such as urokinase and low molecular heparin. (3) To regulate blood lipids and stabilize plaque to prevent aggravation of vascular lesions, statins can be used, commonly used drugs include simvastatin and so on. 2. Surgical treatment: If the patient’s lesions are serious, especially the coronary artery, aorta, renal artery and limb arteries have obvious lumen narrowing or occlusion, interventional or surgical treatments such as stent implantation, bypass grafting and so on can be taken. 3. Control risk factors, such as low-salt and low-fat diet, control blood pressure, blood glucose, blood lipids, quit smoking and drinking, maintain regular aerobic exercise suitable for their own conditions, reduce weight and keep a good mood. Patients with atherosclerosis need to consult the hospital in time, under the guidance of the doctor systematic treatment, so as not to delay the condition.