Perianal abscesses usually hurt, but the exact degree of pain is related to the severity of the condition, in general, when the condition is serious, changing the medicine is more painful than when the condition is less serious. Perianal abscess refers to acute purulent infection in the soft tissues around the rectum and anal canal or in the interstitial space around it, and the formation of abscesses, which can appear as hard lumps, swelling, redness and other symptoms around the anus. Changing the medication when a perianal abscess is present will usually irritate the abscess, so it will hurt. If the perianal abscess is mild, the pain is not very obvious; if the perianal abscess is more serious, the pain is more obvious or even severe. If you find a perianal abscess, it is recommended that you should seek medical treatment in time, and be treated by a professional doctor after formulating a scientific treatment plan in order to prevent the condition from being delayed.