For infant perianal eczema, relief can be provided through general treatment, medication and home care. 1. General treatment: Doctors need to have an in-depth understanding of the patient’s working environment and dietary habits, and to look for potential causes of the disease and conduct a comprehensive examination of the whole body. Do not scratch the lesion excessively, keep the lesion dry and clean. 2. Medication: Infant perianal eczema can be treated with antihistamine drugs such as oral loratadine and cetirizine, and topical application of weak glucocorticosteroid lactinide cream, which can play an anti-inflammatory and antipruritic role. In the secondary bacterial infection, can be applied mupirocin cream and other drugs anti-infection treatment. 3. Family care: usually pay more attention to the cleanliness of the perianal area of the baby, to avoid external stimuli, to prevent the aggravation of the condition, and at the same time to strictly comply with the doctor’s instructions for medication, regular review, to understand the effect of treatment. The above medication should be used under the guidance of a doctor, avoid self-medication to avoid adverse effects.