After drinking alcohol the next day stomach hard to vomit is mostly due to alcohol stimulation of the gastrointestinal mucosa, generally do not need to take special treatment measures. Or may be indigestion, gastritis and other diseases, need to take medication for the cause of the disease, such as domperidone, multienzyme tablets, rabeprazole and so on. 1. Alcohol stimulates the gastrointestinal mucosa: Since alcohol is a kind of stimulating food, when too much alcohol is ingested, it may stimulate the gastrointestinal mucosa, resulting in mucosal congestion. Some people may experience symptoms such as stomach discomfort, nausea, and vomiting, which are mostly normal. Generally drink more water, eat more fresh fruits and vegetables, after a period of rest can be relieved. 2. Indigestion: The next day after drinking alcohol, the stomach is difficult to vomit may also be due to indigestion. Patients can follow the doctor’s instructions to take oral gastrointestinal power drugs, such as domperidone, mosapride. Or digestive enzyme preparations, such as multi-enzyme tablets, yeast tablets. 3. Gastritis: After drinking wine the next day stomach difficult to vomit is also considered to be due to gastritis. The patient can be under the guidance of the doctor oral acid inhibitors and gastric mucosal protection agents, such as rabeprazole, lansoprazole, aluminum thioglycollate and so on. There are many reasons for the patient to have a hard stomach and want to vomit the next day after drinking wine, it is recommended to go to the regular hospital, identify the cause of the disease and take active treatment measures.