Acyclovir can’t treat lichen planus, lichen planus is mostly treated with a combination of topical medication, systemic medication and physical therapy. Lichen planus is a kind of idiopathic inflammatory skin disease, there is no effective treatment at present, most of the comprehensive treatment. Acyclovir is an antiviral drug and cannot be used to treat lichen planus. 1. Topical medication: glucocorticoid ointment, 0.1% retinoic acid ointment, etc., can also be applied to local closed treatment. Vesicular oral damage can be treated with lidocaine gargle to relieve the symptoms. 2. Systemic medication: severe itching can be treated with antihistamines, such as loratadine, etc.; hypertrophic or generalized lesions can be treated with oral glucocorticosteroids, such as prednisone, etc., or oral retinoids, such as Avian A, etc.; if the patient is not sensitive to glucocorticosteroids or stubborn, immunosuppressant agents such as chloroquine, etc., and biologics such as alfacalpine, etc., can also be applied. 3. Physical therapy: photochemotherapy or narrow-spectrum medium-wave ultraviolet radiation can be used. If you are diagnosed with lichen planus, you should consult a doctor in time and standardize the treatment under the guidance of a professional physician, don’t use medication on your own to avoid adverse effects.