The treatment methods for advanced pituitary microadenoma include drug treatment and surgical treatment, radiotherapy and so on. 1. Drug treatment: commonly used drugs include dopamine agonists and growth hormone antagonists. The drugs should be used under the guidance of doctors. (1) Dopamine agonists: such as bromocriptine and cabergoline are used to inhibit the synthesis and secretion of prolactin and return the level of prolactin to normal. It is suitable for patients with prolactin cell adenoma and growth hormone cell adenoma. (2) Growth hormone antagonists: such as octreotide, lanreotide, etc., used to inhibit the secretion of growth hormone and cell proliferation, applicable to patients with growth hormone cell adenoma. 2. Surgical treatment: commonly used surgical methods include transnasal pterygoid sinus pituitary microadenoma resection and open pituitary microadenoma resection. (1) Transnasal sinus pituitary microadenomectomy: the tumor can be removed through the nasal cavity into the skull. (2) Open pituitary microadenomectomy: the skull is opened and the tumor is removed under direct visualization. (3) Radiotherapy: killing tumor cells by gamma knife irradiation, suitable for patients with residual surgery, insensitivity to drugs and those who cannot tolerate surgery. If you are diagnosed with advanced pituitary microadenoma, it is recommended to actively seek treatment to minimize the adverse effects of the disease.