Total protein of 85.9 is not necessarily hepatitis B. The total protein of 85.9 is indeed high, but it is not a definite diagnosis of hepatitis B. In the diagnosis of hepatitis B, it is often based on the epidemiological history of the patient, signs and symptoms, and all kinds of professional examinations. 1. Epidemiological history: at present, the main ways of transmission of hepatitis B virus include mother-to-child transmission, blood and body fluids transmission, which need to be considered according to the patient’s usual life situation and the mother’s disease in the family. 2. Signs and symptoms: the patient has long time weakness, discomfort in liver area, greasiness, spider nevus and so on. 3. Relevant examination: patients can undergo professional examination such as hepatitis B penta and hepatitis B virus nucleic acid, etc. Patients often have triple or triple positive in penta examination, and hepatitis B virus nucleic acid test is positive. The total protein 85.9 test result alone cannot accurately determine whether it is hepatitis B or not, but also needs to be combined with the characteristics of the medical history and other test results to make an accurate judgment, it is recommended to clarify the cause of the disease under the guidance of the doctor.