Leukotriene Modulators Representative Drugs

Leukotriene receptor antagonists, represented by the drugs Proust, Menglust, Zarust. Leukotriene receptor antagonist is a contractile effect on human bronchial smooth muscle, which is about 1000 times stronger than histamine and platelet activating factor. It stimulates mucus secretion, increases vascular permeability, and promotes the formation of mucosal edema, and is currently a commonly used drug in the treatment of allergic rhinitis, and allergic asthma. Characterized by leukotriene receptor modulators are non-hormonal anti-inflammatory drugs, and anti-inflammatory effect is not as strong as hormones, but it has the advantage of oral medication is easy to use, does not contain hormones with few side effects. It is now well established that the use of receptor antagonists or synthetic inhibitors can improve asthma symptoms and dilate airways. Numerous experiments have shown that leukotriene receptor antagonists, have a very important role in improving symptoms.