If you get up every morning with a headache, it may be caused by frontal sinusitis, which usually occurs in adolescent patients and is mainly caused by a cold that does not heal for a long time. In the acute stage, patients are mainly treated with anti-inflammatory drugs, such as ceftriaxone sodium, cefoperazone sulbactam and also metronidazole, tinidazole or ornidazole. In the chronic stage, patients can be treated with puncture irrigation, and in severe cases, surgery can be considered. Patients in the chronic stage can experience memory loss, inattention and thought disorders, and can be treated with oral olanzapine, piracetam, and cytarabine to improve brain metabolism. In general patients with sinusitis, including maxillary sinusitis and mandibular sinusitis, maxillary sinusitis mandibular sinusitis mainly manifests as a strong headache in the afternoon, and frontal sinusitis generally manifests as a strong headache in the morning or morning.