Rhabdomyolysis causes liver damage mainly due to the presence of large amounts of muscle proteins and myosin in the urine, which is easy to cause liver damage when belonging to the body fluid insufficiency or acidic environment. Rhabdomyolysis is caused by a variety of factors that lead to rhabdomyosin cell damage, impaired cell membrane integrity, causing leakage of cell contents, which can be life-threatening in severe cases, mainly in the muscle area. When rhabdomyolysis is severe, there is too little fluid or alkaline substance in the body, and it is in a state of long-term deficiency. Toxins in the body cannot be excreted and accumulate in the liver, destroying liver cells and causing liver damage. After the occurrence of rhabdomyolysis, it is recommended to go to the hospital in time to reduce the damage to the liver, correct electrolyte disorders in time, and return to normal life.