Acute epiglottitis is relatively curable, but needs timely and standardized treatment, otherwise it can also be life-threatening. When acute epiglottitis attacks, we should immediately use a sufficient amount of antibiotics, such as penicillin, cefaclor, etc. for anti-infection treatment, and at the same time use a sufficient amount of glucocorticoid drugs such as dexamethasone and other anti-inflammatory treatment, and at the same time with the local nebulization treatment, such as inhalation of gentamicin, dexamethasone, alpha chymotrypsin and other drugs. In most patients, acute epiglottitis gradually improves after timely treatment with medications. If patients with acute epiglottitis still have severe respiratory distress after drug treatment, tracheotomy or cricothyrotomy should be taken in time to prevent the epiglottis from swelling and blocking the respiratory tract causing asphyxiation, which may lead to death of the patient. Acute epiglottitis patients should go to the hospital in a timely manner, under the guidance of the doctor, the first use of drug treatment, can not be at home on their own medication, to prevent the disease from progressing and threatening the patient’s life.