If the pregnancy is less than 40 days old, with low progesterone and no fetal buds or heartbeat, conservative observation is possible. If the pregnancy is more than 40 days, low progesterone and no fetal buds and fetal heart, usually there is no hope. 1. Gestational time less than 40 days: generally in 40-50 days of gestation will appear buds, 50-60 days of gestation will appear fetal heart, therefore, if in 40 days of labor and delivery, generally fetal heart and fetal buds have not yet formed, and at the same time, progesterone may also be in the lower level, it is recommended that we can consider the treatment of fertility preservation, commonly used drugs, including progesterone capsule. 2. Pregnancy time is greater than 40 days: If the pregnancy time has exceeded 40 days, at this time the pregnancy test still does not suggest the emergence of fetal buds, fetal heart, and low progesterone, the hope of continuing the pregnancy is small. It is recommended to take mifepristone tablets and other drugs under the guidance of a doctor to promote the discharge of pregnancy products in the uterine cavity, or through the scraping operation and other timely removal of residual pregnancy in the uterine cavity. Therefore, if no fetal heart, fetal buds, and low progesterone levels are detected during early pregnancy, medication can be considered for fetal preservation and observation if the pregnancy is within 40 days of gestation; if the pregnancy has exceeded 40 days, there is little hope of continuing the pregnancy, and it is recommended that timely medical attention be given to the doctor’s guidance in order to avoid damage to the pregnant woman’s body.