The most common cause of vaginal tingling is vaginitis and pelvic inflammatory disease, which are easily infected by external bacteria. When bacteria multiply in the vagina, it can cause vaginal congestion, edema and exudate caused by inflammation, which can stimulate the sensory nerves and cause vaginal tingling. Secondly, it may be a foreign body growing in the vagina. The incidence of various malignant tumors and cancers is increasing year by year, and tumors can grow in the vaginal area, if there are tumor cells proliferating in the vaginal opening, it may also stimulate the sensory nerves in the vagina and cause tingling in the vaginal opening, which is the earliest clinical symptom. Thirdly, because of the endocrine disorder in women, the hormone types and contents in the body are richer. Hormones in the body reach the whole body with blood circulation, if the hormone content in women’s body changes, it may also stimulate the mucous membrane of the skin at the vagina and cause stinging pain at the vaginal opening.