During appendicitis surgery, no pain is felt because of the anesthesia, but after the anesthesia wears off, pain is felt and can be treated with pain medication and anti-infection. Currently, patients with appendicitis are usually treated with laparoscopic minimally invasive appendectomy surgery, which requires general anesthesia for the procedure. The anesthesiologist adjusts the dosage of anesthesia medication to the individual patient before and during the surgery, so that the patient does not feel pain, which helps the surgery go smoothly. After the anesthesia has worn off, the patient can gradually feel the pain at the operation site, which is generally tolerable and can be relieved by semi-recumbent position. If the pain is intolerable, pain relieving drugs can be used, such as pethidine, fentanyl, dihydrocodeine, etc., and the doctor can be asked to examine the patient to decide the next step if necessary. Postoperative routine need intravenous application of ceftriaxone sodium, levofloxacin and other antibiotic treatment. It is recommended that the patient cooperate with the doctor to actively carry out the surgery and postoperative rehabilitation, and follow the doctor’s instructions to avoid blind use of drugs.