There are side effects of spot spotting. The reason is that spotting is usually done through chemical drugs, and the corrosive effect of the drugs is used to eliminate some spots on the face. If the spots are located in the stratum corneum and superficial parts of the skin, the spots or patches can be effectively removed by this method. However, if the spots and patches are located deeper, such as in the deep epidermis or superficial dermis, this method is not advisable. This will easily cause local damage to the skin, and in serious cases, it may cause local scarring, or even certain pigment cell mutations, such as precancerous lesions. Especially for some pigmented nevi and melasma, if this chemical drug is used for drip and corrosion, it is easy to induce some cell mutation reactions.