Vomiting one year after total gastrectomy is considered to be caused by tumor recurrence, esophageal anastomotic stenosis, etc. It may also be caused by the adverse reaction of medication, the former needs targeted treatment under the guidance of the doctor, such as medication, surgical treatment, etc., and the latter can be treated with antiemetic medication if necessary. 1. Disease factors: the formation of surgical scar after total gastrectomy will lead to pyloric edema and stenosis, which can’t empty the food after eating and lead to vomiting; scarring stenosis caused by local dilatation, such as endoscopic balloon dilatation, placing a stent, etc., or scar incision for treatment. Vomiting caused by tumor recurrence requires tumor resection again, combined with radiotherapy if necessary. 2. Adverse drug reaction: gastric cancer patients after total gastrectomy may have vomiting symptoms in the process of using chemotherapeutic drugs, and if necessary, they can be given symptomatic treatment such as tropisetron hydrochloride to stop vomiting and ondansetron. Patients who have vomiting one year after total gastrectomy are recommended to go to the hospital for consultation, and ask the doctor to make judgment according to the specific situation and give treatment measures.