Cytomegalovirus retinitis can be clinically diagnosed by a history of immunocompromised disease and typical manifestations of the fundus, and requires an ocular anterior chamber puncture and atrial cytomegalovirus PCR testing to confirm the diagnosis. The main treatment is intraocular injection of antiviral drugs, and early treatment is more effective. What are the symptoms of cytomegalovirus retinitis? The main symptoms of cytomegalovirus retinitis are fixed black shadows in front of the eyes, blurred vision, dark spots, or loss of vision. Cytomegalovirus retinitis occurs only in immunocompromised people, such as AIDS patients and post-transplant patients, but not in normal people. Are people with AIDS susceptible to cytomegalovirus retinitis? Cytomegalovirus retinitis is a major cause of blindness in AIDS patients. It is caused by the failure to effectively inhibit cytomegalovirus replication in the retina due to decreased immunity, resulting in the destruction of retinal tissue cells and the appearance of “cheese + ketchup”-like changes that gradually expand the scope of the lesion and eventually lead to blindness. The disease can be effectively controlled by timely treatment with intraocular antiviral drug injections.