Bupivacaine hydrochloride colloid belongs to local anesthetic drugs, which are mostly used for lubrication and anesthesia in various cavity examinations or surgeries in clinic. Bupivacaine hydrochloride gelatin is mainly composed of bupivacaine hydrochloride, which can act on the peripheral nerves and play the role of analgesia and anesthesia, and it can also play the role of lubrication when applied to the mirror of the microscopic examination. Gastroscopy, butylcaine hydrochloride gel paste can be dropped on the root of the patient’s tongue, to play the role of anesthesia. Urology in the outpatient cystoscopy can be done in the urethra bupivacaine hydrochloride gel paste can be played through the urethra, to play the effect of anesthesia and lubrication. A small amount of bupivacaine hydrochloride gelatin paste can be used on the dilator during proctoscopy to provide lubrication. The use of bupivacaine hydrochloride colloid is contraindicated in patients with allergies or luminal rupture or exposed blood vessels, and the drug is clinically well tolerated, with very few allergic and other adverse reactions. The drug should not be used together with alkaline medicines in order not to reduce the efficacy. If there is a need to use the drug, it is recommended to go to a regular hospital and use it under the guidance of a doctor.