The pus of the granuloma is considered to be caused by the continuous aggravation of the disease, this phenomenon, you need to combine the local situation through the application of oral medication and other methods of treatment, if it is more serious, you may also need to take surgical treatment. If you have a pus-filled wheal, don’t squeeze it with your hands to avoid intracranial infections caused by the backflow of pus. This phenomenon can use medical swabs to clean out the local pus, local use of povidone-iodine or saline cleaning, cleaning and then use antibiotic treatment, such as levofloxacin eye drops or erythromycin ophthalmic ointment treatment. If necessary, you also need to take oral erythromycin, cefixime and metronidazole and other antibiotics. If there is severe localized pain, ibuprofen can also be taken for pain relief. If there is a lot of pus and the above treatment does not improve the situation, it is necessary to consult a doctor to drain the pus through surgical incision. When using medication, you must follow the doctor’s instructions, do not blindly use your own medication, in order to avoid adverse consequences.