Peristaltic pain may be related to indigestion, acute gastroenteritis, gastric cancer, etc. It can be treated by domperidone, montelukast, amoxicillin and surgery. 1. Dyspepsia: Itopride hydrochloride, domperidone and other drugs can be taken to enhance the power of gastrointestinal tract, and can also be combined with large hawthorn pills, gastrointestinal elimination tablets and other drugs, in order to promote digestion, accelerate gastric emptying, and then relieve gastrointestinal peristaltic pain. 2. Acute gastroenteritis: when severe diarrhea manifests itself, it can take Saccharomyces boulardii and montelukast, and when the pain is obvious, it can temporarily use pivacyl bromide and other antispasmodic pain relievers, and if it is combined with bacterial infections, it can take antibiotics, such as levofloxacin tablets and amoxicillin to control the inflammation. 3. Gastric cancer: there are irregular abdominal pain, loss of appetite, emaciation and anemia, etc. Early gastric cancer patients can be cured by surgery, as well as medicines, radiotherapy and other methods of treatment. In addition, patients should pay attention to consume easy-to-digest porridge in daily life and temporarily reduce the amount of food in order to achieve gastrointestinal decompression. There are many other causes of gastrointestinal peristaltic pain, so it is recommended to go to regular hospitals in time for consultation, and after clarifying the causes of the disease, carry out targeted treatment under the guidance of doctors in order to minimize the adverse effects of the disease.