Degenerative diseases commonly occur when the number of parenchymal cells decreases, or when tissues and organs that have developed normally appear to shrink in size and atrophy, preferably in muscle, liver and adrenal cells, and in some nerve cells. There are physiological atrophy, which occurs with age, and many organs and tissues of the human body, including pubertal atrophy of muscles and thymus, and post-menopausal atrophy of the reproductive system, etc. Disuse atrophy is due to long-term workload reduction and low function of organs and tissues, such as muscle atrophy in people who are sedentary, which are all degenerative diseases. In addition, some endocrine atrophy, such as pituitary gland ischemia leads to adrenal gland atrophy, brain and heart aging, in which there are nerve cells and cardiac muscle cells atrophy, etc..