If the test is still positive after three months of HPV infection, those with lesions need general measures, medication, other treatments, and surgery. However, for those without lesions, no treatment is needed. 1. General measures: patients need to strengthen physical exercise, adjust the diet structure, reasonable combination of meals, to ensure a balanced intake of various nutrients, so as to enhance physical fitness and improve immunity. At the same time, it is necessary to pay attention to the hygiene of the skin. 2. Drug treatment: At present, there is no specific drug for HPV infection. Patients can use cytotoxic drugs such as fluorouracil and exfoliators such as vitamin A. Some patients need to use interferon α, imiquimod and other immunomodulatory drugs as prescribed by the doctor. 3. Other treatments: clinically, the treatment can also be carried out by laser, liquid nitrogen freezing, microwave, high-frequency electrocautery and photodynamic and other physical measures, which to a certain extent can remove the lesion tissue. 4. Surgery: For patients who do not need the above treatments or who have high-level intraepithelial lesions in the genital tract, surgical resection should be considered. For patients who are still positive after three months of HPV infection but have no lesions, no special treatment is needed for the time being, and they should continue to be followed up on a regular basis. To summarize, it is recommended that patients with HPV infection should go to the hospital in time, strengthen their daily life management, and cooperate with doctors for active treatment.